Troponin- T Qualitative

This test is useful for aiding in the exclusion of the diagnosis of acute coronary syndrome in a single plasma specimen, in the diagnosis of acute coronary syndrome, monitoring acute coronary syndromes and estimating prognosis and possible utility in monitoring patients with nonischemic causes of cardiac injury. Troponin T is a myofibrillar protein found in striated musculature. There are 2 types of myofilament: a thick filament containing myosin and a thin filament consisting of 3 different proteins, namely actin, tropomyosin, and troponin. Troponin is itself a complex of 3 protein subunits, which are termed troponin T, troponin I, and troponin C. Troponin T is found in free cytosol and structurally bound protein. The unbound pool of troponin T is the source of early protein release in myocardial damage. Troponin T is released from the structural elements at a later stage, corresponding to the degradation of myofibrils that occurs in irreversible myocardial damage. Troponin T becomes elevated 2 to 4 hours after the onset of myocardial necrosis and can remain elevated for up to 14 days, or even longer on occasion
The most common cause of cardiac injury is myocardial ischemia, ie, acute myocardial infarction. These patients are known to have an adverse short- and long-term prognosis compared to patients with unstable angina and no elevation of troponin T. Many of these patients, especially those with troponin T elevations above 30 pg/mL, benefit from an aggressive strategy with anticoagulation and an invasive interventional strategy.

Troponin- T Qualitative rate list in Delhi NCR: